Principal Investigator
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Dr. Sangpil Yoon
Position: Assistant Professor (Full Bio_Click) Department of Aerospace and Mechanical Engineering Email: syoon4@nd.edu Google Scholar: Click here Education PhD, Mechanical Engineering, The University of Texas at Austin, 2012 MS, Aerospace Engineering, Georgia Institute of Technology, 2004 BS, Mechanical Engineering, Yonsei University, 2002 |
Biography
Dr. Sangpil Yoon joined the Department of Aerospace and Mechanical Engineering in 2018. Prior to July 2018, he was a research associate in the Department of Biomedical Engineering at University of Southern California. He received his Bachelor’s degree in Mechanical Engineering from Yonsei University, Seoul Korea and Master’s degree in Aerospace Engineering from Georgia Institute of Technology. He earned his Ph.D. in Mechanical Engineering from the University of Texas at Austin. At UT-Austin, Dr. Yoon developed a technique to measure mechanical properties of soft tissue quantitatively using a laser-induced microbubble interrogated by acoustic radiation force under the direction of Professor Stanislav Emelianov. He joined Professor Kirk Shung’s lab at University of Southern California to develop ultrasonic transducers and intravascular ultrasound (IVUS) imaging system. As a postdoc fellow, he developed dual element IVUS imaging transducers to obtain both high and low frequency information from a single scan to better detect vulnerable atherosclerotic plaques. He developed ultra high frequency ultrasonic transducers for cellular applications. He studied biophysical effects of high frequency ultrasound to single cells including mechanotransduction and intracellular delivery of macromolecules. He has developed a new intracellular delivery technique using high frequency ultrasound and was awarded a Pathway to Independence Award (K99/R00) from the NIH. He is a member of IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society, Biomedical Engineering Society, and Acoustical Society of America.
Summary of Activities/Interests
I research on diagnosis and therapy in cancer. For diagnosis, we are developing a ultrasound contrast agent. Ultrasound is directly applicable to in vivo imaging due to deep penetration depth. For therapeutic strategies, we are developing a device by integrating a microfluidic chip and ultrasonic transducers to engineer cells, such as T cells, to express specific biomarkers to increase anti-tumor activity. By engineering those cells in vitro, we can reinfuse those engineered cells into a patient’s body to treat cancers. With my research, I hope to improve the quality of life for many people with better cancer treatments and even cures.
Dr. Sangpil Yoon joined the Department of Aerospace and Mechanical Engineering in 2018. Prior to July 2018, he was a research associate in the Department of Biomedical Engineering at University of Southern California. He received his Bachelor’s degree in Mechanical Engineering from Yonsei University, Seoul Korea and Master’s degree in Aerospace Engineering from Georgia Institute of Technology. He earned his Ph.D. in Mechanical Engineering from the University of Texas at Austin. At UT-Austin, Dr. Yoon developed a technique to measure mechanical properties of soft tissue quantitatively using a laser-induced microbubble interrogated by acoustic radiation force under the direction of Professor Stanislav Emelianov. He joined Professor Kirk Shung’s lab at University of Southern California to develop ultrasonic transducers and intravascular ultrasound (IVUS) imaging system. As a postdoc fellow, he developed dual element IVUS imaging transducers to obtain both high and low frequency information from a single scan to better detect vulnerable atherosclerotic plaques. He developed ultra high frequency ultrasonic transducers for cellular applications. He studied biophysical effects of high frequency ultrasound to single cells including mechanotransduction and intracellular delivery of macromolecules. He has developed a new intracellular delivery technique using high frequency ultrasound and was awarded a Pathway to Independence Award (K99/R00) from the NIH. He is a member of IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society, Biomedical Engineering Society, and Acoustical Society of America.
Summary of Activities/Interests
I research on diagnosis and therapy in cancer. For diagnosis, we are developing a ultrasound contrast agent. Ultrasound is directly applicable to in vivo imaging due to deep penetration depth. For therapeutic strategies, we are developing a device by integrating a microfluidic chip and ultrasonic transducers to engineer cells, such as T cells, to express specific biomarkers to increase anti-tumor activity. By engineering those cells in vitro, we can reinfuse those engineered cells into a patient’s body to treat cancers. With my research, I hope to improve the quality of life for many people with better cancer treatments and even cures.